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Decentralized science (DeSci) protocols are where decentralized finance (DeFi) was in 2019 — nascent and untested in the markets but possessing “massive potential,” an industry executive said.&nbsp;
“Everything is still raw, experimental, but there’s an underlying understanding [...] that there is massive potential,” <a data-ct-non-breakable="null" href="https://x.com/Rewkang/status/1860722553326850398" rel="null" target="null" text="null" title="null">said</a> Andrew Kang, a founder and partner at crypto-focused venture capital firm Mechanism Capital, in a Nov. 24 post on X. 
Kang said the DeSci projects are evolving and will likely change their models and products like DeFi protocols Maker, Synthetix and Aave did around 2019 before they expanded.
The DeSci projects Kang has found most interesting are BIO Protocol, Pump Science and GLP1. 
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 <img alt="Science, Medicine, Coronavirus" src="https://s3.cointelegraph.com/uploads/2024-11/019360de-e7b9-758d-9090-12d848a1321d" title="">
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 Source: <a data-ct-non-breakable="null" href="https://x.com/Rewkang/status/1860722553326850398" rel="null" target="null" text="null" title="https://x.com/Rewkang/status/1860722553326850398">Andrew Kang</a>
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BIO Protocol allows users to co-own “medicines of the future,” Pump Science’s platform allows trading of tokens tied to longevity medicines and GLP1 aims to “Make America Skinny Again.”
Kang disclosed that Mechanism Capital invested in BIO Protocol’s <a data-ct-non-breakable="null" href="https://cointelegraph.com/news/binance-labs-invests-in-bio-protocol" rel="null" target="null" text="null" title="null">latest funding round.</a>
DeSci is a concept that utilizes blockchain technology and aspects of it, such as tokens, NFTs and decentralized autonomous organizations (DAOs) to incentivize community-driven scientific research and collaboration.&nbsp;
it is looking to do everything from solving flaws in <a data-ct-non-breakable="null" href="https://cointelegraph.com/news/blockchain-based-desci-solves-science-peer-review-problem-charles-hoskinson" rel="null" target="null" text="null" title="null">science’s peer review system</a> and <a data-ct-non-breakable="null" href="https://cointelegraph.com/news/people-pay-a-huge-price-for-their-genetics-but-de-sci-has-a-solution-edited" rel="null" target="null" text="null" title="null">getting cheaper genetic tests</a> to even <a data-ct-non-breakable="null" href="https://cointelegraph.com/news/science-desci-baldness-medicine-decentralization" rel="null" target="null" text="null" title="null">curing baldness.</a>
DeSci is primarily focused on pursuing truth via “citizen science” while rejecting institutional influences such as Big Pharma.
The industry emerged from the COVID-19 pandemic as industry players looked for new and improved ways to fight off infection and disease.
Related: <a data-ct-non-breakable="null" href="https://cointelegraph.com/news/decentralized-science-can-be-the-next-big-thing-for-blockchain-utilization" rel="null" target="null" text="null" title="null">Decentralized science can be the next big thing for blockchain utilization</a>
It may make data more accessible to researchers, health-care professionals and their patients while leveraging the security and transparency benefits of blockchain.
It comes as cybersecurity attacks in healthcare have become increasingly common in the digital age.
<a data-ct-non-breakable="null" href="https://cointelegraph.com/news/chainalysis-crypto-hack-ransom-rise-2024" rel="null" target="null" text="null" title="null">Ransomware attacks</a> on health-care firms such as<a data-ct-non-breakable="null" href="https://www.reuters.com/technology/cybersecurity/kaiser-notifies-millions-data-breach-2024-04-25/" rel="null" target="null" text="null" title="null"> Kaiser</a> and Welltok have affected 13.4 million and 8.49 million individuals in separate incidents in the past 18 months — exposing sensitive personal and health-related information.
DeSci currently boasts a $1.2 billion market cap, led by OriginTrail (TRAC) at $374.9 million, followed by Rifampicin (RIF) and VitaDAO (VITA) at $133.1 million and $124.7 million, <a data-ct-non-breakable="null" href="https://www.coingecko.com/en/categories/decentralized-science-desci" rel="null" target="null" text="null" title="null">according</a> to CoinGecko.
<figure>
 <img alt="Science, Medicine, Coronavirus" src="https://s3.cointelegraph.com/uploads/2024-11/019360de-42ec-7b45-b7e6-f797ce159b16" title="">
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 Top 10 largest DeSci tokens by market cap. Source: CoinGecko
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Magazine: <a data-ct-non-breakable="null" href="https://cointelegraph.com/magazine/desci-tokens-help-improve-scientific-research/" rel="null" target="null" text="null" title="null">DeSci: Can crypto improve scientific research?</a>

Decentralized science is like early DeFi in 2019: Crypto VC

Cointelegraph

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